Alternative Therapy for T1DM - Pancreatic Transplantations

Document Type

Presentation

Publication Date

2026

Abstract

Over the past summer, I completed the Diabetes Institute Summer Interprofessional Research Experience (DISIRE) Internship at Ohio University, where I investigated the mechanisms and complications of Type 1 Diabetes Mellitus (T1DM). I worked there to analyze previously formulated therapeutic compounds, while I created personal compounds to test their effects as well. T1DM is an autoimmune disease characterized by the destruction of healthy pancreatic beta-cells, resulting in long-term insulin dependence. Through this experience, I gained a strong understanding of the metabolic and immunological challenges associated with the disease, along with the limitations of exogenous insulin therapy. Shadowing an endocrinologist further deepened my appreciation for the complexity of diabetes management and highlighted the need for more sustainable treatment options. I gained some experience in treating underserved populations through my contributions on a medical missionary trip to the Dominican Republic, allowing for a better understanding of long-term disease management. As a Type 1 diabetic, I was inspired to explore pancreatic transplantation, including both whole-organ and islet-cell approaches, as alternative therapies. My research involved reviewing current scholarly studies to evaluate the efficacy, benefits, and limitations of transplantation compared to standard care. This work contributes to a broader understanding of regenerative medicine and the potential for transplantation to improve long-term outcomes in individuals with T1DM.

This document is currently not available here.

Open Access

Available to all.

Share

COinS