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Pharmacy and Wellness Review

Abstract

Diabetes is an endocrine disease caused by deficiency or malfunction of insulin that results in high blood glucose levels and places patients at higher risk for a number of complications. This chronic disease is difficult to manage and affects millions of people in the United States, costing the health care system billions of dollars a year. Of a variety of antidiabetic agents used to control blood glucose, insulin is perhaps the most effective, but until recently it was only available in injectable form. As of June 27, 2014, a new inhaled insulin called Afrezza® (Technosphere® insulin) was approved by the U.S. Food and Drug Administration (FDA) and will soon be coming to market. This rapid-acting insulin is administered through the lungs and offers an alternative to traditional dosage forms. This article further explores some background about Technosphere® insulin, its mechanism of action and literature regarding its efficacy.

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