Pharmacy and Wellness Review
Abstract
Alcohol use disorder (AUD) is a medical condition that arises from the inability to control alcohol consumption regardless of negative consequences. Over 10% of the US population met the diagnostic criteria for having AUD in 2022.1 Each individual presents with symptoms of AUD differently and may therefore need more personalized treatment. Research has shown that using a combination of currently available pharmacological and non-pharmacological treatment options provides the best results for patients with AUD. However, there still remains a pressing need for the development of newer treatment options. Psilocybin, a naturally occurring psychedelic compound, is currently under investigation due to its potential therapeutic benefits in various neuropsychiatric illnesses. While there has been an increase in research regarding psilocybin’s clinical application, little is known about its efficacy in the AUD patient population. Currently, only one clinical trial has been completed evaluating the effectiveness of psilocybin in AUD. The results of the trial concluded that psilocybin produced statistically significant outcomes compared to placebo for patients with AUD, including a reduction in heavy drinking days and some instances of abstinence. However, completion of additional studies is needed to further strengthen the evidence for the use of psilocybin in AUD.
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Homeopathy Commons, Pharmaceutical Preparations Commons, Psychiatric and Mental Health Commons, Psychoanalysis and Psychotherapy Commons, Substance Abuse and Addiction Commons